Neuro protedtive effects of lycopene and Tetracarpidium conophorum Extract on Heat -Stressed Cockerels
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Date
2024-06-01
Journal Title
Journal ISSN
Volume Title
Publisher
Badeggi Journal
Abstract
bstract
The study was conducted to determine the neuro protective potential of lycopene and Tetracarpidium conophorum
leave Extract (TCLE) on acetyl cholinesterase activity and oxidative status of heat-stress cockerels. A total of 54
cockerels of 25- week old were used for this experiment. There were nine treatments: 0 ml of extract/ 250 ml of
water (control)(T1), 30 ml of lycopene/250 ml of water (T2), 60 ml of lycopene/250 ml of water (T3), 30 ml of
TCLE/250 ml of water (T4), 60 ml of TCLE /250 ml of water (T5), 15 ml of lycopene + 15 ml of TCLE/250 ml of
water (T6), 30 ml of lycopene + 30 ml of TCLE/ 250 ml of water (T7), Vitamin C 0.1g/250 ml of water (T8), Cooler
temperature (25±2
o
C (T9). Total Protein (TP), brain antioxdant; superoxide peroxidase (SOD),
catalase (CAT), Glutathione peroxidase (GPx), Glutathiones-S transferase (GST), Glutathione (GSH),
Malondialdehyde (MDA) Acetylcholinesterase (AChe) and phytochemical quantitative/ qualitative analysis of
TCLE were evaluated.Results showed that value obtained for crude protein (7.24%), moisture (4.66%), ash and
crude fibre content (9.75% and 2.49%) of TCL were depressed, while carbohydrate value (65.30%) was elevated.
Also TCLE contain essential compounds as saponin, tannin, phenolics, flavonoids, alkaloids, steroids, glycosides,
coumarins, triterpenes, terpenoids and fixed oils, which are present in low quantity(+). There was non-significant
effect (P>0.05) of lycopene and Tetracarpidium conophorum on TP, MDA, SOD and catalase of cockerel brain,
however, significant elevation was observed in the brain GST was significantly elevated treatment 4 (1490.45 U/mg
protein), GPx (1009.04 U/mg protein), GSH (71.03 U/mg protein) and Acetylcholinesterase activities were
significantly (P<0.05) influenced by the treatments. It was observed that the experimental inclusions did not
significantly impose any negative effect on the cockerels.
Description
As a way of exploring ameliorative solution, there has been a frequent use of phyto-derived natural antioxidants such as lycopene produced
from fresh tomatoes and Tetracarpidium conophorum leaves (TLC), having similar activities with synthetic antioxidants (Yashin et al., 2013). This study is therefore designed to evaluate the efficacy of tomatoes and Tetracarpidium conophorum leaves on the neuro protective effect of cockerels under stress.
Keywords
Citation
Ojo O.A. Akintunde A.O, Jimoh O.A and Braje M.S 2024. Neuro protective effects of lycopene and Tetracarpidiu, Conophorum extracts on heat-stressed cockerels Badeggi Journal of Agricultural Research & Environment 6(1),1-12 Publisher: The Badeggi Journal of Agricultural Research & Environment. https://doi.org/10.35849/BJARE202401/125/001. https://www.ncribjare.org/portal/index.php/bjare/article/view/125