Neuro protedtive effects of lycopene and Tetracarpidium conophorum Extract on Heat -Stressed Cockerels

dc.contributor.authorOlayinka Abosede Ojo
dc.contributor.authorAdeyinka Akintunde
dc.contributor.authorAbubarkar Jimoh
dc.contributor.authorBaraje M.S
dc.date.accessioned2024-08-03T20:27:42Z
dc.date.available2024-08-03T20:27:42Z
dc.date.issued2024-06-01
dc.descriptionAs a way of exploring ameliorative solution, there has been a frequent use of phyto-derived natural antioxidants such as lycopene produced from fresh tomatoes and Tetracarpidium conophorum leaves (TLC), having similar activities with synthetic antioxidants (Yashin et al., 2013). This study is therefore designed to evaluate the efficacy of tomatoes and Tetracarpidium conophorum leaves on the neuro protective effect of cockerels under stress.
dc.description.abstractbstract The study was conducted to determine the neuro protective potential of lycopene and Tetracarpidium conophorum leave Extract (TCLE) on acetyl cholinesterase activity and oxidative status of heat-stress cockerels. A total of 54 cockerels of 25- week old were used for this experiment. There were nine treatments: 0 ml of extract/ 250 ml of water (control)(T1), 30 ml of lycopene/250 ml of water (T2), 60 ml of lycopene/250 ml of water (T3), 30 ml of TCLE/250 ml of water (T4), 60 ml of TCLE /250 ml of water (T5), 15 ml of lycopene + 15 ml of TCLE/250 ml of water (T6), 30 ml of lycopene + 30 ml of TCLE/ 250 ml of water (T7), Vitamin C 0.1g/250 ml of water (T8), Cooler temperature (25±2 o C (T9). Total Protein (TP), brain antioxdant; superoxide peroxidase (SOD), catalase (CAT), Glutathione peroxidase (GPx), Glutathiones-S transferase (GST), Glutathione (GSH), Malondialdehyde (MDA) Acetylcholinesterase (AChe) and phytochemical quantitative/ qualitative analysis of TCLE were evaluated.Results showed that value obtained for crude protein (7.24%), moisture (4.66%), ash and crude fibre content (9.75% and 2.49%) of TCL were depressed, while carbohydrate value (65.30%) was elevated. Also TCLE contain essential compounds as saponin, tannin, phenolics, flavonoids, alkaloids, steroids, glycosides, coumarins, triterpenes, terpenoids and fixed oils, which are present in low quantity(+). There was non-significant effect (P>0.05) of lycopene and Tetracarpidium conophorum on TP, MDA, SOD and catalase of cockerel brain, however, significant elevation was observed in the brain GST was significantly elevated treatment 4 (1490.45 U/mg protein), GPx (1009.04 U/mg protein), GSH (71.03 U/mg protein) and Acetylcholinesterase activities were significantly (P<0.05) influenced by the treatments. It was observed that the experimental inclusions did not significantly impose any negative effect on the cockerels.
dc.description.sponsorshipself-sponsored
dc.identifier.citationOjo O.A. Akintunde A.O, Jimoh O.A and Braje M.S 2024. Neuro protective effects of lycopene and Tetracarpidiu, Conophorum extracts on heat-stressed cockerels Badeggi Journal of Agricultural Research & Environment 6(1),1-12 Publisher: The Badeggi Journal of Agricultural Research & Environment. https://doi.org/10.35849/BJARE202401/125/001. https://www.ncribjare.org/portal/index.php/bjare/article/view/125
dc.identifier.issn2695-2122
dc.identifier.urihttps://kwasuspace.kwasu.edu.ng/handle/123456789/2143
dc.language.isoen
dc.publisherBadeggi Journal
dc.titleNeuro protedtive effects of lycopene and Tetracarpidium conophorum Extract on Heat -Stressed Cockerels
dc.typeArticle
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