Fermented Rice Water for Biosynthesis of Silver Nanoparticles (AgNPs) and its Antimicrobial Activities against Microorganisms Associated with Skin Infection
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Date
2023-06
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Publisher
The Nigerian Society for Microbiology (NSM
Abstract
As a skin treatment, rice water is becoming increasingly popular. It is said to aid in the treatment
of a variety of skin ailments. Despite the fact that rice water has some genuine benefits, science has yet to
fully validate many of its claims. The aim of this study is to biosynthesize nanoparticles using fermented
rice water and to carry out the antimicrobial activity of the synthesized nanoparticles. To synthesize the
silver nanoparticles, rice was subjected to a 48-hour fermentation process to obtain fermented rice water
(FRW), which served as a bio-reductant and stabilizer for the nanoparticle synthesis and was used as the
antimicrobial agents. UV-Visible spectroscopy was used to characterize the particles. The antimicrobial
potential of FRW-AgNPs was assessed against common clinical bacterial and fungal isolates associated
with skin diseases and infections (Staphylococcus aureus, Candida albicans and Trichophyton rubrum).
The inhibitory effects of FRW-AgNPs were compared to those of FRW alone. The colloidal AgNPs were
brownish in color and had a maximum absorption wavelength of 380nm, indicating that nanoparticles had
formed. FRW-AgNPs demonstrated antimicrobial activity against Staphylococcus aureus and Candida
albicans strains, inhibiting their growth with inhibitory zones measuring 21.3 mm and 22.0 mm,
respectively. In contrast, FRW displayed lower inhibitory effects, with inhibitory zones of 13.3 mm and
13.0 mm against the respective strains highlighting the enhanced antibacterial and antifungal activity of
FRW-AgNPs compared to FRW alone. Additionally, FRW-AgNPs completely inhibited the growth of
Trichophyton rubrum at a concentration of 100 µg/ml. This study successfully biosynthesized silver
nanoparticles using fermented rice water and demonstrated their promising antimicrobial properties against
clinically relevant fungal strains associated with skin disease and infection.