Neuro Protective Effect of Lycopene and Tetracarpidium Conophorum Extracts on Heat-Stressed Cockerels
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Date
2024-06-01
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Badeggi Journals
Abstract
The study was conducted to determine the neuro protective potential of lycopene and Tetracarpidium conophorum
leave Extract (TCLE) on acetyl cholinesterase activity and oxidative status of heat-stress cockerels. A total of 54
cockerels of 25- week old were used for this experiment. There were nine treatments: 0 ml of extract/ 250 ml of
water (control)(T1), 30 ml of lycopene/250 ml of water (T2), 60 ml of lycopene/250 ml of water (T3), 30 ml of
TCLE/250 ml of water (T4), 60 ml of TCLE /250 ml of water (T5), 15 ml of lycopene + 15 ml of TCLE/250 ml of
water (T6), 30 ml of lycopene + 30 ml of TCLE/ 250 ml of water (T7), Vitamin C 0.1g/250 ml of water (T8), Cooler
temperature (25±2
o
C (T9). Total Protein (TP), brain antioxdant; superoxide peroxidase (SOD),
catalase (CAT), Glutathione peroxidase (GPx), Glutathiones-S transferase (GST), Glutathione (GSH),
Malondialdehyde (MDA) Acetylcholinesterase (AChe) and phytochemical quantitative/ qualitative analysis of
TCLE were evaluated.Results showed that value obtained for crude protein (7.24%), moisture (4.66%), ash and
crude fibre content (9.75% and 2.49%) of TCL were depressed, while carbohydrate value (65.30%) was elevated.
Also TCLE contain essential compounds as saponin, tannin, phenolics, flavonoids, alkaloids, steroids, glycosides,
coumarins, triterpenes, terpenoids and fixed oils, which are present in low quantity(+). There was non-significant
effect (P>0.05) of lycopene and Tetracarpidium conophorum on TP, MDA, SOD and catalase of cockerel brain,
however, significant elevation was observed in the brain GST was significantly elevated treatment 4 (1490.45 U/mg
protein), GPx (1009.04 U/mg protein), GSH (71.03 U/mg protein) and Acetylcholinesterase activities were
significantly (P<0.05) influenced by the treatments. It was observed that the experimental inclusions did not
significantly impose any negative effect on the cockerels
Description
A critical study of the cockerel brain is paramount as it controls physical gesturing, maintenance of the balance of the animal or subject, regulation of muscle tension and the function. Therefore, any damage to the brain is a damage to the whole animal, there is therefore an urgent need to proffer solution to this impending problem.
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Citation
Ojo O.A. Akintunde A.O, Jimoh O.A and Braje M.S 2024. Neuro protective effects of lycopene and Tetracarpidiu, Conophorum extracts on heat-stressed cockerels Badeggi Journal of Agricultural Research & Environment 6(1),1-12 Publisher: The Badeggi Journal of Agricultural Research & Environment. https://doi.org/10.35849/BJARE202401/125/001. https://www.ncribjare.org/portal/index.php/bjare/article/view/125