Phytochemicals, proximate and elemental analysis, antioxidant and cytotoxic potentials of purple (Capitata F. rubra) and green (Capitata Linn.) Brassica oleraceae (cabbage)
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Date
2024-05-25
Journal Title
Journal ISSN
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Publisher
Journal of Pharmacy and Bioresources
Abstract
Malnutrition remains a significant impediment to growth in many countries. Exploring the medicinal potentials of
exotic vegetables represents a strategic approach to achieving sustainable development goals. This study focused on
the evaluation of proximate, elemental, and phytochemical composition, including the antioxidant and cytotoxic
potentials of green and purple cabbage varieties. The findings revealed different percentages of moisture, crude fat,
fibre, protein, and carbohydrates in both varieties. Calcium, magnesium, potassium, sodium, iron, copper, zinc,
saponins, terpenoids, flavonoids, phenolics, tannins, anthraquinones, and steroids were also detected and quantified.
The green (IC50=186.3 μg/mL) and purple (IC50=187.6 μg/mL) cabbage extracts demonstrated broad-spectrum 2,2-
diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity, as compared with the standard, ascorbic acid
(IC50=267 μg/mL). Similarly, the green (IC50=148.7 μg/mL) and purple (IC50=103.9 μg/mL) cabbage extracts
exhibited nitric oxide inhibitory activity, as compared with the standard, ascorbic acid (IC50=135.2 μg/mL). The green
(CC50=10.6 μg/mL) and purple (CC50=16.66 μg/mL) cabbage extracts exhibited an inhibition on the growth of
Rhabdomyosarcoma cell lines as compared with the standard, Vincristine (CC50=0.30 μg/mL). These results support
the utilization of the two cabbage varieties as dietary supplements, potentially aiding in the discovery of anticancer
drugs and the management of other disease conditions owing to their antioxidant properties.