COMPARATIVE EVALUATION OF DISINFECTANT EFFECTIVENESS ON CLINICAL BACTERIAL ISOLATES IN A DISK DIFFUSION STUDY
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Date
0030-12-24
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Journal ISSN
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Publisher
Applied Environmental Bioscience and Public Health Research Group,University of Benin, Benin City, Nigeria
Abstract
This study aimed to assess the efficacy of various disinfectants on clinical bacterial isolates with a focus on
Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia and Pseudomonas aeruginosa. The clinical
isolates were subjected to testing with four disinfectants: Phenols, Formaldehyde, Sodium hypochlorite, and
Ethyl alcohol, utilizing the disk-diffusion method. Pathogenic bacteria pose a significant threat, capable of inducing a
range of symptoms that can vary from mild to severe and potentially life-threatening, affecting both individuals and
other organisms. The widespread use of disinfectants to mitigate microbial growth on inanimate objects highlights the
importance of understanding their effectiveness. Formaldehyde emerged as the most effective disinfectant, exhibiting a
92% susceptibility pattern, while Phenol demonstrated an 8% susceptibility. In contrast, sodium hypochlorite and ethyl
alcohol presented no area of inhibition against any of the clinical bacterial isolates. Specific susceptibility patterns were
observed, with Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus, proving susceptible to
Formaldehyde at rates of 41%, 32%, and 27%, respectively. Conversely, Klebsiella pneumonia demonstrated resistance
to Formaldehyde. These findings highlight the variable efficiency of the tested disinfectants. Given the superior efficacy
of Formaldehyde against the bacterial isolates, routine testing of disinfectants is recommended to ensure their
effectiveness against pathogenic microorganisms.