ANTIMICROBIAL STUDY OF SOME TRANSITION METAL COMPLEXES OF RHODANINE AND SALICYLADIMINE
Loading...
Date
2018-09-10
Journal Title
Journal ISSN
Volume Title
Publisher
Asian Journal of Basic and Applied Science
Abstract
In this study, complexes of copper and zinc with rhodanine and salicyladimine were examined
for their antimicrobial properties against selected bacteria species. The complexes were also
characterized using infra-red and ultra-violet spectroscopy for structural elucidation and
determination of electronic transitions occurring between the ligands and their complexes. All
the complexes showed varied inhibition on the growth of the test organisms at different
minimum inhibitory concentrations ranging from 0 – 25 mg/ml. The infra-red spectroscopy
showed the presence of different functional groups like O-H stretching vibration at 3441cm-1, C-
H bending at 833.28cm-1 and 750.33cm-1, C=C stretching vibration at 2360.95cm-1 in the
salicyladimine ligand and N-H stretching vibration at 3448.84cm-1 in the complex formed with
copper, whereas Rhodanine shows C=O at 1734cm-1 with copper acetate, 1708.99cm-1 with Zinc
nitrate, C-H stretching at 3086.21cm-1, 3074.63cm-1 with copper and 3174.94cm-1 with zinc. The
ultraviolet spectroscopy showed absorptions assigned to different geometry. The complex of
salicylaldimine showed two bands around 26385 cm-1 and 42016 cm-1 which are assigned to
square planar geometry. Rhodanine showed four bands around 48780 cm-1, 33898 cm-1, 39525
cm-1 corresponding to n→π* transition and 26809 cm-1 corresponding to n→σ* transition.
Rhodanine complex with zinc nitrate showed two bands around 23925cm-1 and 22411cm-1
assigned to charge transfer. Rhodanine complexed with copper acetate showed two bands around
20283 cm-1 and 24096 cm-1 which are assigned to square planar geometry. From the analysis of
variance, there is no significant difference (p-value= 0.05) in the antibacterial activity and the
selected pathogen. Based on this study, we recommend that metal complexes should be used to
restrict the growth of bacteria in place of Ligands