Antimycotic and phytochemical screening of the fruit pulp extract of Tamarind (Tamarindus indica) on Can dida albican
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Date
2016
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Abstract
Objective: To determine the antimycotic potency of
the aqueous and ethanolic extract of the fruit pulp of
Tamarindus indica on human pathogenic Candida al bicans.
Methods: The disk diffusion method was employed to
check for the antimycotic potency of extracts while
qualitative and quantitative analysis of some phyto chemical constituents was carried out following stand ard methods.
Results: The fruit pulp extracts were effective against
the organism at 475 and 485 mg/ml in the aqueous and
ethanolic extract respectively. The same concentration
served as the Minimum Inhibitory and Minimum Fun gicidal Concentration (MIC and MCC) in both extracts.
The extracts were also subjected to qualitative and
quantitative phytochemical analysis. Alkaloids, tan nins and reducing sugars were found in the ethanol ex tract while in the aqueous extract glycosides, saponins
and reducing sugars were discovered to be present.
Conclusions: The study indicated that aqueous and eth anolic extracts of the fruit pulp of T. indica can be a
potential source of antimycotic agent to combat the
challenge of the emergence of drug-resistance in Can dida albicans and the need to produce more effective
antimicrobial agents.
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Adedayo et al JOURNAL OF MICROBIOLOGY AND ANTIMICROBIAL AGENTS. 2016; 2 (1): 16-2