Coordination Compounds of n-phthaloylglycine and n-phthaloyltyrosine and their antimicrobial activities.
| dc.contributor.author | Adedibu, C. Tella, Stephen O. Oguntoye, Osunniran, W. A. and Rotimi O. Arise | |
| dc.date.accessioned | 2025-02-05T11:01:51Z | |
| dc.date.available | 2025-02-05T11:01:51Z | |
| dc.date.issued | 2012-03-28 | |
| dc.description.abstract | Coordination compounds derived from N-phthaloylglycine and N-phthaloyltyrosine were synthesized. The ligands were formed by 1:2 molar condensation of phthalic anhydride with tyrosine and glycine respectively. The complexes were formulated as [Zn(PHG)2 (H2O)2] (OAc)2[1], [Ni(PHG)2 (H2O)2] (OAc)2 [2] and [Cu(PHT)2 ] (OAc)2 [3] characterized by melting point, conductivity, AAS , IR, Uv-Visible spectroscopies. Both ligands were found to be bidentate. For complexes [1] and [2] the metal ions coordinate through both oxygen of OH and C=O in the carboxylic group to give octahedral geometry whereas in the [3] the coordination of metal ion occurs through both oxygen of phenoxyl and carbonyl group resulting in tetrahedral geometry. The antimicrobial studies using four test organisms(P.aerugenosa, E.Coli, S. aureus and C. albicans) revealed that the metal complexes exhibit higher activity than their respective ligands. | |
| dc.identifier.citation | Adedibu, C. Tella, Stephen O. Oguntoye, Osunniran, W. A. and Rotimi O. Arise (2012). Coordination Compounds of n-phthaloylglycine and n-phthaloyltyrosine and their antimicrobial activities. Elixir Appl. Chem, 45: 7620 – 7623. Published by Elixir International Journal (Photonics). Available online at https://www.elixirpublishers.com/ | |
| dc.identifier.other | https://www.elixirpublishers.com/ | |
| dc.identifier.uri | https://kwasuspace.kwasu.edu.ng/handle/123456789/3984 | |
| dc.language.iso | en | |
| dc.title | Coordination Compounds of n-phthaloylglycine and n-phthaloyltyrosine and their antimicrobial activities. | |
| dc.type | Article |