Department of Microbiology

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Browsing Department of Microbiology by Author "Abdulmumini S.A."

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    Fermented Rice Water for Biosynthesis of Silver Nanoparticles (AgNPs) and its Antimicrobial Activities against Microorganisms Associated with Skin Infection
    (The Nigerian Society for Microbiology (NSM, 2023-06) Yusuf-Salihu B.O; Abdulmumini S.A.; Ajao A.T
    As a skin treatment, rice water is becoming increasingly popular. It is said to aid in the treatment of a variety of skin ailments. Despite the fact that rice water has some genuine benefits, science has yet to fully validate many of its claims. The aim of this study is to biosynthesize nanoparticles using fermented rice water and to carry out the antimicrobial activity of the synthesized nanoparticles. To synthesize the silver nanoparticles, rice was subjected to a 48-hour fermentation process to obtain fermented rice water (FRW), which served as a bio-reductant and stabilizer for the nanoparticle synthesis and was used as the antimicrobial agents. UV-Visible spectroscopy was used to characterize the particles. The antimicrobial potential of FRW-AgNPs was assessed against common clinical bacterial and fungal isolates associated with skin diseases and infections (Staphylococcus aureus, Candida albicans and Trichophyton rubrum). The inhibitory effects of FRW-AgNPs were compared to those of FRW alone. The colloidal AgNPs were brownish in color and had a maximum absorption wavelength of 380nm, indicating that nanoparticles had formed. FRW-AgNPs demonstrated antimicrobial activity against Staphylococcus aureus and Candida albicans strains, inhibiting their growth with inhibitory zones measuring 21.3 mm and 22.0 mm, respectively. In contrast, FRW displayed lower inhibitory effects, with inhibitory zones of 13.3 mm and 13.0 mm against the respective strains highlighting the enhanced antibacterial and antifungal activity of FRW-AgNPs compared to FRW alone. Additionally, FRW-AgNPs completely inhibited the growth of Trichophyton rubrum at a concentration of 100 µg/ml. This study successfully biosynthesized silver nanoparticles using fermented rice water and demonstrated their promising antimicrobial properties against clinically relevant fungal strains associated with skin disease and infection.