Department of Chemistry and Industrial Chemistry
Permanent URI for this community
Browse
Browsing Department of Chemistry and Industrial Chemistry by Author "Ajiboye, Abdulfatai Temitope"
Now showing 1 - 4 of 4
Results Per Page
Sort Options
- ItemPhysicochemical Analyses of Coconut (Cocos nucifera L.) Oil Obtained by Solvent (Aqueous and n-Hexane) Extraction Methods(2024-02-28) Bale, Adebayo Tajudeen; Ajiboye, Abdulfatai Temitope; Idiaro, Isiaka AyobamiThe oil of coconut (cocos nucifera L.) was extracted by two different processing methods; aqueous (heating method) and solvent (soxhlet) extraction method. The physicochemical properties of the oil extracts were evaluated. The results showed that the density, specific gravity, viscosity and pH (aqueous extraction; 0.89 g/cm3, 0.91, 4.0 mpa.s, 4.7 and solvent extraction; 0.89 g/cm3, 0.91, 3.8 mpa.s, 5.1 respectively) of the oil extracts were relatively close. Other properties like the saponification value, free fatty acid, acid value and peroxide value of the aqueous and solvent extraction methods are 196.35 mgKOH/g, 0.56 mgKOH/g, 0.00028 mgKOH/g, 0.2 meq peroxide/g and 266.4 mgKOH/g, 0.95 mgKOH/g, 0.0047 mgKOH/g, 2.0 meq peroxide/g respectively.
- ItemSorption Study of Cd(II) from Aqueous Solution Using Activated Carbon Prepared from Vitellaria paradoxa Shell(2015) Bale, Adebayo Tajudeen; Jimoh, Akeem Adebayo; Adebayo, G.B; Otun, K.O; Ajiboye, Abdulfatai Temitope; Jamiu, W.; Alao, F.OActivated carbon prepared from vitellaria paradoxa (shea nut) shell using ortho-phosphoric acid has been used for the removal of Cd(II) ion from aqueous solution. The adsorbent sample was characterized by some physicochemical and spectroscopic parameters such as pH, point of zero charge (PZC), moisture content, iodine number, loss on ignition, bulk density, XRF, SEM and TEM. The pH and the PZC of the sample were found to be 4.0 and 5.8 respectively. The adsorbent sample has moisture content of 5.22 ± 0.1%, iodine number of 456.50 ± 59%, loss on ignition 10.71 ± 0.18% bulk density of 0.84 ± 0.09%. The XRF analysis indicated that Ca, Si and Fe were major constituents in the adsorbent sample. The SEM and TEM analysis results indicated good adsorptive characteristics of the adsorbent. Result from the FTIR analysis indicate presence of some important components such as C=O, O-H, C-O N-H, and P-H which responsible for high adsorptive capacity of the adsorbent. The equilibrium adsorption of Cd(II) ion data was well fitted with Langmuir and Freundlich isotherms with correlation coefficient of 0.996 and 0.998 respectively. The kinetic study revealed that pseudo-second order kinetic was better fitted compared to pseudo-first order kinetic. Thermodynamic experiment indicated that the adsorption process was exothermic with ∆H equals +27.84 KJ/mol and ∆S equals -0.993 KJ/molK.
- ItemSynthesis, Characterization and α-Amylase Inhibition Study of Substituted Schiff Base and Its Metal Complexes(2023-12-31) Bale, Adebayo Tajudeen; Osunniran, Wahab Adesina; Ajiboye, Abdulfatai TemitopeMechanochemical synthesis is considered as a green and sustainable approach to chemical reactions since it requires little or no solvent, making the process more environmentally friendly by reducing waste and minimizing solvent related hazards. In this study, substituted Schiff base was synthesized from 2-aminophenol and 2- hydroxy-1-naphthaldeyde via mechanochemical synthesis method. The metal complexes were synthesized by reacting the ligand with metal(II) chlorides in ratio 2:1. The synthesized compounds were characterized by colour, melting point, molar conductivity, FT-IR, and UV-Vis spectroscopy. The ligand and its metal complexes were screened for α-amylase inhibitory activity. FT-IR results showed absorption bands in between the ranges 1628-1632 cm-1 and 1585-1597 cm-1 indicating the formation of azomethine C=N and aromatic C=C respectively. The metal complexes showed M-O absorption bands in between the range 519-579 cm-1 and M-N band in between the range 461-484 cm-1. The synthesized compounds displayed significant inhibitory activities (IC50: 2.00-8.43 mg/mL) against α-amylase comparable to the reference compound, acarbose (IC50: 9.12 mg/mL). These compounds can serve as viable templates in the formulation of new active antidiabetic drugs.
- ItemThe Studies of Antioxidant and Antimicrobial Potentials of the Leaf Extract of Bauhinia monandra Plant(Longdom Publishing SL, 2015) Bale, Adebayo Tajudeen; Ajiboye, Abdulfatai Temitope; Musa, MD; Otun, KO; Jimoh, Akeem Adebayo; Lawal, SO; Arowona, MTIn the present study, the dried leaf (144g) of B. monandra plant was extracted with 95% ethanol. The crude extract was partitioned into ethyl acetate and n-hexane layers to afford fractions with golden brown and greenish yellow colours respectively. The fractions were concentrated and coded EFBM and HFBM. The preliminary phytochemical screening conducted on the crude extract and ethyl acetate fraction (EFBM) revealed the presence of flavonoids, tannins, steroids, terpenoids, saponin, cardiac glycoside and phenols. The antioxidant activity of EFBM and HFBM was evaluated using DPPH radical scavenging assay with ascorbic acid as a reference standard. However, the result of analysis revealed that EFBM exhibited high antioxidant (IC50 µg/mL=0.010) activity than HFBM (IC50 µg/m = 5.564) and reference standard ascorbic acid (IC50 µg/mL=30). The antibacterial activity of EFBM and HFBM against three gram negative bacterial strains (Eschericha coli, Pseudomonas aeruginosa and Klebsillia oxytoca) was also evaluated and it was found that EFBM exhibited highest antibacterial potential. In contrast to this, HFBM showed negligible or zero activity against all the bacteria strains. The results of the GC-MS analyses of EFBM and HFBM showed the presence of nine different phytochemicals. In EFBM, oleic acid which is classified as monounsaturated omega-9-fatty acid with percentage concentration, (40.76%) was the major compound as identified by the GC-MS and 4-hydroxy-5-methyl-3-propyl-2-hexanone with percentage concentration, (42.70%) was identified as the major compound in HFBM. The results of this studies demonstrated that folk medicine can be as effective as modern medicine to combat pathogenic microorganisms. The millenarian use of the leaf of this plant in folk medicine suggests that it represents an economic and safe alternative to treat infectious diseases.