Histological Response of Clariasgariepinus to Varying Concentrations of Pharmaceutical Effluents
| dc.contributor.author | Akinpelu, A. T., Akinloye, O. M., Olayinka, A. S., Opasola, O. A., Stephen, O. A., and Oluwaseun, O. T. | |
| dc.date.accessioned | 2025-02-08T16:01:30Z | |
| dc.date.available | 2025-02-08T16:01:30Z | |
| dc.date.issued | 2019-01-13 | |
| dc.description | Water quality can be described as the physical, chemical, biological and aesthetic properties of water, which determine its fitness for use and consumption, and its ability to maintain the integrity and health of an ecosystem [1]. Increasing contamination of the aquatic environment worldwide has been associated with improper discharge of solid wastes, industrial, medical and agricultural effluents [2-4]. Pharmaceutical effluents contain mixture of various classes of organic and inorganic micro pollutants that are capable of inducing toxicological effects on aquatic organisms. There are several reports on the presence of pharmaceuticals and their metabolites in most aquatic environments worldwide [5-7]. | |
| dc.description.abstract | For the past few decades, environmental pollution is considered a major global problem for public health and this problem has continued to impact aquatic environment. Pharmaceutical discharges are major sources of pollution that poses serious threat to aquatic animals like fish, therefore, this work aimed at evaluating the histological architecture of the gill tissues of Clarias gariepinus on exposed to sub-lethal concentrations of pharmaceutical effluents using standard laboratory procedure. The physicochemical characteristics of the pharmaceutical effluent used revealed varied level of deviations from World Health Organization standard for waste discharge into any Original Research Article Akinpelu et al.; ARRB, 35(4): 68-75, 2020; Article no.ARRB.49531 69 categories of water bodies. The histological studies of the sectioned gills of the exposed fish showed varied level of histological alterations which are concentrations dependent. The observed histopathological lesions recorded include infiltration of secondary lamellae, inter-lamellae hyper plastic lesion, and oedema, congestion of the blood vessels, epithelial thickening and lifting, and necrosis of various degrees. All the fish held in the control stock showed inappreciable or no histological degradation and their staining patterns and cellular arrangement remained unaffected and this showed that even low concentration of such effluent is enough to induce physiological imbalances in aquatic organisms. The degrees of all these recorded anomalies were concentration dependent. Therefore, indiscriminate disposal of this effluent is detrimental to aquatic community and to combat this, strict compliance of the laws with total vigilance against illegal discharge of effluent should be enacted and enforced. | |
| dc.description.sponsorship | SELF | |
| dc.identifier.citation | 12.Akinpelu, A. T., Akinloye, O. M., Olayinka, A. S., Opasola, O. A., Stephen, O. A., and Oluwaseun, O. T. (2020). Histological Response of Clarias gariepinus to Varying Concentrations of Pharmaceutical Effluents. Annual Research and Review in Biology, 35(4), 68-75. | |
| dc.identifier.issn | 2347-565X | |
| dc.identifier.uri | https://kwasuspace.kwasu.edu.ng/handle/123456789/4077 | |
| dc.language.iso | en_US | |
| dc.publisher | Annual Research & Review in Biology | |
| dc.relation.ispartofseries | 35(4); 68-75 | |
| dc.title | Histological Response of Clariasgariepinus to Varying Concentrations of Pharmaceutical Effluents | |
| dc.type | Article |