Antibacterial Activities of Methanol and Ethanol Extracts of Moringa oleifera (Lam) Leaves
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Date
2024
Journal Title
Journal ISSN
Volume Title
Publisher
Jewel Journal of Scientific Research , Federal University of Kashere-Nigeria
Abstract
Moringa oleifera is known for its therapeutic potential, particularly in treating bacterial infections.
This study aimed to determine the Minimum Inhibitory Concentrations (MIC) and Minimum
Bactericidal Concentration (MBC) of Moringa oleifera extracts (ethanol and methanol) on two
bacterial strains: Escherichia coli (gram-negative) and Staphylococcus aureus (gram-positive). The
extracts were tested at concentrations of 200, 150, 100, 50, and 25 mg/ml. Phytochemical analysis
was also conducted. Results showed that Moringa extracts exhibited significant antibacterial
activity, with the methanol extract showing an MIC and MBC of 200 mg/ml, and the ethanol extract
showing an MIC and MBC of 150 mg/ml. The zones of inhibition were 19 mm (E. coli) and 18 mm
(S. aureus) for methanol extract, and 18 mm (E. coli) and 17 mm (S. aureus) for ethanol extract.
These results were similar to those of Ciprofloxacin (a standard antibiotic), indicating that Moringa
extracts have strong antimicrobial properties. The study suggests that Moringa oleifera could be
used as an alternative or adjunct to conventional antibiotics. Future studies should explore the
synergistic effects of combining Moringa extracts with existing antibiotics to enhance their
effectiveness and combat antibiotic resistance.