Effect of nano-encapsulated ginger on the physiological response, oxidative status and hormonal profile of rabbits reared in the tropics

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dc.contributor.authorO.A. Ojo
dc.date.accessioned2026-06-19T10:50:53Z
dc.date.available2026-06-19T10:50:53Z
dc.date.issued2023
dc.description.abstractThe nano-encapsulation technology of phytogenic bio-components is a new technology employed to solve the unstability challenge associated with phytonutrients, when used as a phytogenic component generally and in animal studies. Incidence of global warming have resulted into heat stress, adversely affecting animal health and performance. Application of phytogenic bioactive components, such as the ones found in ginger has proven positive, this is because ginger (Zingiber officinale Roscoe) contains gingerols, specifically 6- gingerol, which is an active compound, noted to contain strong antioxidant activity. However, the instability of phytonutrients in the gut necessitated adoption of nanotechnology, incorporated into phytochemistry to ameliorate heat stress and improve animal performance. This research was conducted to evaluate the effectiveness of nano-encapsulated ethanolic ginger extract on the physiological response, oxidative status and hormones of rabbit does in the tropics. Sixty-four nulliparous (7-months-old) pure line breeders (New Zealand White Rabbit does), averagely weighing 23kg, aged between four to six (4–6) months were used. Experimental does were randomly allocated to four treatment groups at 16 does per treatment. Experimental design is as follows; Group 1 received 3mls of water, Group 2 - 50mg/kg body weight of non encapsulated ginger extract in 3mls of water. Group 3- 10mg/kg body weight of nano-encapsulated ginger extract in 3mls of water. Group 4- 25mg/kg body weight of nano-encapsulated ginger extract in 3mls of water. Blood was collected via marginal ear vein, serum separated through centrifugation. triodothyronine, tetraiodothyronine and luteinizing hormone were analyzed using commercial solid-phase enzyme immuno-assay kits. It was noted that at week 4, respiratory rate, ear temperature, heart rate and rectal temperature (100.25±1.47, 100.44±1.45, 24.66±1.30, and 24.76±1.37) were significantly (P<0.05) lowered in treatment group 4, administered with 25mg/kg nano-encapsulated ginger, in comparison to other treatment groups. All oxidative parameters evaluated were not significantly influenced by the experimental supplementation of nano-encapsulated ginger. However, 10mg/kg body weight of nano-encapsulated ginger administration lmproved the luteinizing hormone concentration of test animals under treatment group 3
dc.identifier.issnhttps://doi.org/10.1016/j.anscip.2023.01.565
dc.identifier.urihttps://kwasuspace.kwasu.edu.ng/handle/123456789/7460
dc.language.isoen
dc.publisherElsevier
dc.titleEffect of nano-encapsulated ginger on the physiological response, oxidative status and hormonal profile of rabbits reared in the tropics
dc.typeArticle
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