Evaluation of Serum Creatine Kinase and Lactate Dehydrogenase Activities in Hypertensive Patients Attending General Hospital Ilorin, Kwara State, Nigeria

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dc.contributor.authorBusari Akeem Olayinka
dc.contributor.authorOnamadi Temitope Ayobami
dc.contributor.authorIbrahim Munirudeen
dc.contributor.authorBalogun Morufu Eyitayo
dc.contributor.authorGarba Wasiu Olanrewaju
dc.contributor.authorOgunwale Kolawole Tajudeen
dc.contributor.authorAdunmo Godwin O.
dc.contributor.authorAhmad Muhammed Bello
dc.contributor.authorMohammed Idris Yahaya
dc.contributor.authorNassar Sulaiman Adebayo
dc.contributor.authorAkinola Franklin Folasele
dc.contributor.authorPopoola Niyi Abdulgafar
dc.contributor.authorLawal Abubakar Zubair
dc.contributor.authorOyeniyi Maroof Gbadebo
dc.contributor.authorEleha Suleiman
dc.date.accessioned2025-01-28T21:16:16Z
dc.date.available2025-01-28T21:16:16Z
dc.date.issued2021-12
dc.description.abstractAbstract The main factor contributing to morbidity and mortality is hypertension. Although blood pressure is a complicated feature, studies have shown that the activity of adenosine triphosphate (ATP)-generating enzymes like creatine kinase (CK) and lactate dehydrogenase (LDH) is a major predictor of hypertension. As a result, this study evaluated the activities of CK and LDH activities in hypertensive patients attending the General Hospital Ilorin, Kwara State. One hundred and sixty-one (161) hypertensive patients and thirty-nine (39) normotensive subjects were recruited into a case-control study of 200 participants. Body mass index (BMI) was estimated from each participant's measured weight and height, while the blood pressure was determined from the measured systolic blood pressure (SBP) and diastolic blood pressure (DBP) using conventional mercury sphygmomanometer. A 5 mls sample of blood was taken from each subject, and the extracted serum was analyzed using an enzymatic-kinetic method to quantify the CK and LDH activities. Results showed that hypertensive patients had significantly at p<0.05 higher serum CK and LDH activities in hypertensive compared to apparently healthy normotensives. Thus, this study observed significantly increase CK and LDH activities in hypertensive patients
dc.identifier.citationBusari, A.O., Onamadi, T.O., Ibrahim, M., Balogun, M.E. Garba, W.O., Ogunwale, K.T., Adunmo, G.O., Ahmad, M.B. Mohammed, I.Y., Nassar, S.A., Akinola, F.F., Popoola, A.N., Lawal, A.Z., Oyeniyi, M.G., Eleha, S. (2021). Evaluation of Serum Creatine Kinase and Lactate Dehydrogenase Activities in Hypertensive Patients Attending General Hospital Ilorin, Kwara State, Nigeria, Al-Hikmah Journal of Health Sciences, 1(1), 1-6.
dc.identifier.issn2811-1516
dc.identifier.issn2811-1524
dc.identifier.urihttps://kwasuspace.kwasu.edu.ng/handle/123456789/3509
dc.language.isoen
dc.titleEvaluation of Serum Creatine Kinase and Lactate Dehydrogenase Activities in Hypertensive Patients Attending General Hospital Ilorin, Kwara State, Nigeria
dc.typeArticle
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