Nasal Carrier of Methicillin-Resistance Staphylococcus Aureus in Apparently Healthy Individuals in Kwara State University, Malete, Nigeria

Abstract
Abstract Infections in hospitals and the general population are frequently caused by Staphylococcus aureus. Methicillin-resistant Staphylococcus aureus is still a significant nosocomial pathogen, and because of its resistance to several medications, infections are frequently hard to treat. As such the study aim to isolate Staphylococcus aureus in nasal carrier of an apparently healthy students in Kwara state university, using standard bacteriological method, and determine the prevalence of MRSA and MSSA from the isolate. The study is a cross-sectional study done to determine the distribution of MRSA among Kwara state university students using a Nasal swab. Microbial isolates were identified based on their colonial morphology and biochemical reaction and antimicrobial susceptibility testing was carried out using Mueller Hinton Agar following the disk diffusion method with cefoxitin disk while the zone of inhibition was recorded using the CLSI standard. A total number of 100 nasal swab samples were collected from 100 apparently healthy students of Kwara state university and were screened for Methiciillin Resistant Staphylococcus aureus. Out of 100 samples screened (50 from males and females participants each), 42 (42%) of the isolates were Staphylococcus aureus based on morphology and biochemical tests. Of the 42 Staphylococcus aureus isolated, 19 (45%) and 23 (55%) was from males and females participant respectively. The prevalence of MSSA and MRSA is 8 (16%) and 11 (22%) respectively among males participant, and 9 (18%) and 14 (28%) respectively among the females participant. The study reported a significant rate of Methicillin-resistant Staphylococcus aureus (MRSA) among the study participants and emphasized the need for Keywords: Methicillin-resistant Staphylococcus aureus (MRSA), Nasal carrier, antimicrobial resistance.
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Citation
Mustapha A, Ogunniyi TJ, Olaide TS, Adekunle CO, Opeyemi AA, Obeagu EI. Nasal Carrier of Methicillin-Resistance Staphylococcus Aureus in Apparently Healthy Individuals in Kwara State University, Malete, Nigeria. Elite Journal of Medicine, 2024; 2(6): 10-21