Browsing by Author "Oluwatobi O. Amusan"

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    A Review on Classes, Extraction, Purification and Pharmaceutical Importance of Plants Alkaloid
    (Journal of Medicinal and Chemical Sciences, 2019-08-18) Hamzat T. Adejoke; Hitler Louis; Oluwatobi O. Amusan; Gloria Apebende
    playsvital role in the prevention and treatments of diseasessuch as cancer, malaria, pile etc. These natural products which include alkaloid, flavonoid, phenol, saponin and tannin are bioactive compounds in plant and essential in plant metabolic activities. All of these have been tested for their huge medicinal properties and therefore could serve as an alternative medicine in treatment of myriad ailments. Although, through the modern-day technologies, these bioactive compounds have been separated from the plants and synthesized into capsules and tablets for easy administration, usage and storage, there is a need to create awareness on the side-effects associated with excess or abuse of medicinal plants and to encourage rational use of natural resources for sustainability. Thus, this review gives an overview on pharmacological importance of named alkaloids, methods of extraction and purification of alkaloids in plant, laying emphasis on side-effects associated to the abuse of alkaloids or alkaloid derivative drugs.
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    Synthesis and characterization of CaO catalyst obtained from achatina achatina and its application in biodiesel production
    (Journal of Medicinal and Nanomaterials Chemistry, 2019-03-12) Oluwatobi O. Amusan; Hitler Louis; Adejoke T. Hamzat; Oluwatomisin F. Oyebanji; Ayodeji T. Alagbe; Thomas O. Magu
    In this research study, Achatina achatina shells was used as the source of raw material to produce calcium oxide which was used as a catalyst in the production of biodiesel. The main aim of this study was to investigate the effect of varying temperatures on the calcium oxide formed using A. achatina during the calcination process for their possible use as a heterogeneous catalyst in the production of biodiesel. The shells were first grinded and then calcinated at different temperatures ranging from 0 °C to 1000 °C. After calcination, the CaCO3 present in the A. achatina shell was converted to calcium oxide. The obtained calcium oxide was characterized using Fourier transform infrared spectroscopy (FT-IR). The asymmetric stretching of the CO32- (cm-1) absorption was not proportional with the increasing temperature as it was observed over the plane vibrational modes of CO32 (cm-1). Also, the O-H stretching band (cm-1) at 100 °C and 800 °C had similar absorption values. Pearson correlation revealed both negative and positive relationship between the absorption rate and the temperature, disclosed a significant difference at p<0.05. The calcined structure was examined using scanning electron microscope (SEM) with a magnification of 10,000X. A more stabilized, uniform structure, and agglomerate into lumps were observed at 800 °C and 1000 °C. The results showed that, the A. achatina shell is a suitable catalyst in the production of Biodiesel because it is readily available and has no adverse effect on the environment.