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  1. Home
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Browsing by Author "Adebiyi, A.A."

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    An Adaptive Genetic Algorithm with Recursive Feature Elimination Approach for Predicting Malaria Vector Gene Expression Data Classification Using Support Vector Machine
    (Walailak University - Walailak Journal of Science and Technology, 2021) Arowolo, M.O.; Adebiyi, M.O.; Nnodim, C.T.; Abdulsalam, S.O.; Adebiyi, A.A.
    As mosquito parasites breed across many parts of the sub-Saharan Africa part of the world, infected cells embrace an unpredictable and erratic life period. Millions of individual parasites have gene expressions. Ribonucleic acid sequencing (RNA-seq) is a popular transcriptional technique that has improved the detection of major genetic probes. The RNA-seq analysis generally requires computational improvements of machine learning techniques since it computes interpretations of gene expressions. For this study, an adaptive genetic algorithm (A-GA) with recursive feature elimination (RFE) (A-GA-RFE) feature selection algorithms was utilized to detect important information from a high-dimensional gene expression malaria vector RNA-seq dataset. Support Vector Machine (SVM) kernels were used as the classification algorithms to evaluate its predictive performances. The feasibility of this study was confirmed by using an RNA-seq dataset from the mosquito Anopheles gambiae. The technique results in related performance had 98.3 and 96.7 % accuracy rates, respectively. Keywords: RNA-seq, Adaptive genetic algorithm, Recursive feature elimination, Malaria vector, Support Vector Machine kernels

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