Browsing by Author "Abubarkar Jimoh"

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    Neuro protedtive effects of lycopene and Tetracarpidium conophorum Extract on Heat -Stressed Cockerels
    (Badeggi Journal, 2024-06-01) Olayinka Abosede Ojo; Adeyinka Akintunde; Abubarkar Jimoh; Baraje M.S
    bstract The study was conducted to determine the neuro protective potential of lycopene and Tetracarpidium conophorum leave Extract (TCLE) on acetyl cholinesterase activity and oxidative status of heat-stress cockerels. A total of 54 cockerels of 25- week old were used for this experiment. There were nine treatments: 0 ml of extract/ 250 ml of water (control)(T1), 30 ml of lycopene/250 ml of water (T2), 60 ml of lycopene/250 ml of water (T3), 30 ml of TCLE/250 ml of water (T4), 60 ml of TCLE /250 ml of water (T5), 15 ml of lycopene + 15 ml of TCLE/250 ml of water (T6), 30 ml of lycopene + 30 ml of TCLE/ 250 ml of water (T7), Vitamin C 0.1g/250 ml of water (T8), Cooler temperature (25±2 o C (T9). Total Protein (TP), brain antioxdant; superoxide peroxidase (SOD), catalase (CAT), Glutathione peroxidase (GPx), Glutathiones-S transferase (GST), Glutathione (GSH), Malondialdehyde (MDA) Acetylcholinesterase (AChe) and phytochemical quantitative/ qualitative analysis of TCLE were evaluated.Results showed that value obtained for crude protein (7.24%), moisture (4.66%), ash and crude fibre content (9.75% and 2.49%) of TCL were depressed, while carbohydrate value (65.30%) was elevated. Also TCLE contain essential compounds as saponin, tannin, phenolics, flavonoids, alkaloids, steroids, glycosides, coumarins, triterpenes, terpenoids and fixed oils, which are present in low quantity(+). There was non-significant effect (P>0.05) of lycopene and Tetracarpidium conophorum on TP, MDA, SOD and catalase of cockerel brain, however, significant elevation was observed in the brain GST was significantly elevated treatment 4 (1490.45 U/mg protein), GPx (1009.04 U/mg protein), GSH (71.03 U/mg protein) and Acetylcholinesterase activities were significantly (P<0.05) influenced by the treatments. It was observed that the experimental inclusions did not significantly impose any negative effect on the cockerels.